Thursday, March 29, 2007

About Transplants

You may have heard about transplants but may not know the process. There are several types cell transplants available to treat patients with blood cancers. Although transplants are used to treat a number of diseases, I have italicized the diseases that are specific to our mission.

Autologous Transplants
Samples of the patient's own bone marrow or peripheral blood stem cells can be removed, frozen and stored to be returned after chemotherapy or radiation therapy. Diseases treated in this manner include:
Brain Tumors
Ewing's Sarcoma
Neuroblastoma
Rhabdomyosarcoma
Hodgkin's Disease
Non-Hodgkin' s Lymphoma

Allogeneic Transplants
In allogeneic transplants, the patient's bone marrow is replaced with marrow from a donor who is either a family member or a matched, unrelated donor. Our doctors provide allogeneic transplants for a wide range of blood diseases, including:
Hematologic Malignancies (Cancers of the Blood)
Acute Lymphoblastic Leukemia
Acute Myelogenous Leukemia
Chronic Myelogenous Leukemia
Juvenile Myelomonocytic Leukemia
Myelodysplastic Syndromes
Non-Hodgkin' s Lymphoma

Genetic Diseases
Hemoglobinopathies:
sickle cell disease
thalassemia
Severe combined immune deficiency
Fanconi's Anemia
Wiskott-Aldrich Syndrome

Other Blood Disorders
Amegakaryocytic Thrombocytopenia
Aplastic Anemia
Diamond Blackfan Anemia
Hemophagocytic Lymphohistiocytosis
Kostmann Syndrome

Types of Transplants
The types of transplants include bone marrow, peripheral blood, and cord blood transplants using HLA-matched sibling donors, unrelated donors, and family mismatched donors.

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